Latest publications

Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis.

  • Neuro-Oncology Laboratory
  • Computational Biomedecine
April 10, 2019
2019 Apr. Acta Neuropathol Commun.7(1):55.
By:
  • Sundstrom T
  • Prestegarden L
  • Azuaje F
  • Aasen SN
  • Rosland GV
  • Varughese JK
  • Bahador M
  • Bernatz S
  • Braun Y
  • Harter PN
  • Skaftnesmo KO
  • Ingham ES
  • Mahakian LM
  • Tam S
  • Tepper CG
  • Petersen K
  • Ferrara KW
  • Tronstad KJ
  • Lund-Johansen M
  • Beschorner R
  • Bjerkvig R
  • Thorsen F.

Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma.

  • Computational Biomedecine
  • NORLUX Neuro-Oncology Laboratory
April 08, 2019
2019 Apr. Neuro Oncol. [Epub ahead of print].
By:
  • Hossain JA
  • Latif MA
  • Ystaas LAR
  • Ninzima S
  • Riecken K
  • Muller A
  • Azuaje F
  • Joseph JV
  • Talasila KM
  • Ghimire J
  • Fehse B
  • Bjerkvig R
  • Miletic H.

Irradiation to improve the response to immunotherapeutic agents in glioblastomas.

  • Neuro-Oncology Laboratory
April 01, 2019
2019 Apr. Adv Radiat Oncol.4(2):268-282.
By:
  • Nesseler JP
  • Schaue D
  • McBride WH
  • Lee MH
  • Kaprealian T
  • Niclou SP
  • Nickers P.

The association between changes in weekly running distance and running-related injury: Preparing for a half marathon.

  • Sports Medicine Research Laboratory
April 01, 2019
2019 Apr. J Orthop Sports Phys Ther.49(4):230-238. Epub 2018 Dec 7.
By:
  • Damsted C
  • Parner ET
  • Sorensen H
  • Malisoux L
  • Hulme A
  • Nielsen RO.

Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide.

  • Tumor Immunotherapy and Microenvironment
  • Neuro-Oncology Laboratory
April 01, 2019
2019 Apr. Int J Cancer.144(7):1735-1745. Epub 2018 Dec 11.
By:
  • Johannessen TC
  • Hasan-Olive MM
  • Zhu H
  • Denisova O
  • Grudic A
  • Latif MA
  • Saed H
  • Varughese JK
  • Rosland GV
  • Yang N
  • Sundstrom T
  • Nordal A
  • Tronstad KJ
  • Wang J
  • Lund-Johansen M
  • Simonsen A
  • Janji B
  • Westermarck J
  • Bjerkvig R
  • Prestegarden L.

HSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells.

  • Tumor Stroma Interactions
April 01, 2019
2019 Apr. Oncogene.38(15):2767-2777. Epub 2018 Dec 12.
By:
  • Causse SZ
  • Marcion G
  • Chanteloup G
  • Uyanik B
  • Boudesco C
  • Grigorash BB
  • Douhard R
  • Dias AMM
  • Dumetier B
  • Dondaine L
  • Gozzi GJ
  • Moussay E
  • Paggetti J
  • Mirjolet C
  • de Thonel A
  • Dubrez L
  • Demidov ON
  • Gobbo J
  • Garrido C.

Temporal dynamics of cortisol-associated changes in mRNA expression of glucocorticoid responsive genes FKBP5, GILZ, SDPR, PER1, PER2 and PER3 in healthy humans.

  • Immune Endocrine and Epigenetics
  • Clinical and Applied Virology
April 01, 2019
2019 Apr. Psychoneuroendocrinology.102:63-67. Epub 2018 Nov 30.
By:
  • Yurtsever T
  • Streit F
  • Foo JC
  • Trifonova S
  • Kumsta R
  • Muller CP
  • Turner JD
  • Meyer J
  • Schote AB.

Achieving integrated care through commissioning of primary care services in the English NHS: a qualitative analysis.

  • Public Health Research
April 01, 2019
2019 Apr. BMJ Open.9(4):e027622.
By:
  • McDermott I
  • Checkland K
  • Moran V
  • Warwick-Giles L.

INFOGEST static in vitro simulation of gastrointestinal food digestion.

  • Public Health Research
April 01, 2019
2019 Apr. Nat Protoc.14(4):991-1014. Epub 2019 Mar 18.
By:
  • Brodkorb A
  • Egger L
  • Alminger M
  • Alvito P
  • Assuncao R
  • Ballance S
  • Bohn T
  • Bourlieu-Lacanal C
  • Boutrou R
  • Carriere F
  • Clemente A
  • Corredig M
  • Dupont D
  • Dufour C
  • Edwards C
  • Golding M
  • Karakaya S
  • Kirkhus B
  • Le Feunteun S
  • Lesmes U
  • Macierzanka A
  • Mackie AR
  • Martins C
  • Marze S
  • McClements DJ
  • Menard O
  • Minekus M
  • Portmann R
  • Santos CN
  • Souchon I
  • Singh RP
  • Vegarud GE
  • Wickham MSJ
  • Weitschies W
  • Recio I.

Metabolically healthy and unhealthy weight statuses, health issues and related costs: Findings from the 2013-2015 European Health Examination Survey in Luxembourg.

  • Public Health Research
  • Competence Center for Methodology and Statistics
April 01, 2019
2019 Apr. Diabetes Metab.45(2):140-151. Epub 2017 Dec 1.
By:
  • Samouda H
  • Ruiz-Castell M
  • Karimi M
  • Bocquet V
  • Kuemmerle A
  • Chioti A
  • Dadoun F
  • Stranges S.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPbeta.

  • Proteomics of cellular signaling
March 29, 2019
2019 Mar. iScience.13:351-370. Epub 2019 Mar 1.
By:
  • Dittmar G
  • Hernandez DP
  • Kowenz-Leutz E
  • Kirchner M
  • Kahlert G
  • Wesolowski R
  • Baum K
  • Knoblich M
  • Hofstatter M
  • Muller A
  • Wolf J
  • Reimer U
  • Leutz A.

Do tumor cells escape from natural killer cell cytotoxicity by mimicking dendritic cells?

  • Cytoskeleton and Cancer Progression
March 29, 2019
2019 Mar. Oncotarget.10(25):2419-2420.
By:
  • Wurzer H
  • Al Absi A
  • Hoffmann C
  • Thomas C.

Catalyzing transcriptomics research in cardiovascular disease: The CardioRNA COST Action CA17129.

  • Cardiovascular Research Unit
March 29, 2019
2019 Mar. Noncoding RNA.5(2).
By:
  • Gomes CPC
  • Agg B
  • Andova A
  • Arslan S
  • Baker A
  • Bartekova M
  • Beis D
  • Betsou F
  • Wettinger SB
  • Bugarski B
  • Condorelli G
  • Silva G
  • Danilin S
  • de Gonzalo-Calvo D
  • Buil A
  • Carmo-Fonseca M
  • Enguita FJ
  • Felekkis K
  • Ferdinandy P
  • Gyongyosi M
  • Hackl M
  • Karaduzovic-Hadziabdic K
  • Hellemans J
  • Heymans S
  • Hlavackova M
  • Hoydal MA
  • Jankovic A
  • Jusic A
  • Kardassis D
  • Kerkela R
  • Kuster GM
  • Lakkisto P
  • Leszek P
  • Lustrek M
  • Maegdefessel L
  • Martelli F
  • Novella S
  • O'Brien T
  • Papaneophytou C
  • Pedrazzini T
  • Pinet F
  • Popescu O
  • Potocnjak I
  • Robinson E
  • Sasson S
  • Scholz M
  • Simionescu M
  • Stoll M
  • Varga ZV
  • Vinciguerra M
  • Xuereb A
  • Yilmaz MB
  • Emanueli C
  • Devaux Y
  • On Behalf Of The Eu-CardioRN A. Cost Action (CA17129).

Graft materials provide greater static strength to medial opening wedge high tibial osteotomy than when no graft is included.

  • Sports Medicine Research Laboratory
March 28, 2019
2019 Mar. J Exp Orthop.6(1):13.
By:
  • Belsey J
  • Diffo Kaze A
  • Jobson S
  • Faulkner J
  • Maas S
  • Khakha R
  • Wilson AJ
  • Pape D.

Earlier initiation of antiretroviral treatment coincides with an initial control of the HIV-1 Sub-Subtype F1 outbreak among men-having-sex-with-men in Flanders, Belgium.

  • HIV Clinical and Translational Research
March 26, 2019
2019 Mar. Front Microbiol.10:613.
By:
  • Vinken L
  • Fransen K
  • Cuypers L
  • Alexiev I
  • Balotta C
  • Debaisieux L
  • Seguin-Devaux C
  • Garcia Ribas S
  • Gomes P
  • Incardona F
  • Kaiser R
  • Ruelle J
  • Sayan M
  • Paraschiv S
  • Paredes R
  • Peeters M
  • Sonnerborg A
  • Vancutsem E
  • Vandamme AM
  • Van den Wijngaert S
  • Van Ranst M
  • Verhofstede C
  • Stadler T
  • Lemey P
  • Van Laethem K.

A DNA repair and cell-cycle gene expression signature in primary and recurrent glioblastoma: prognostic value and clinical implications.

  • DNA Repair and Chemoresistance
  • Computational Biomedecine
  • Neuro-Oncology Laboratory
March 15, 2019
2019 Mar. Cancer Res.79(6):1226-1238. Epub 2019 Jan 23.
By:
  • Gobin M
  • Nazarov PV
  • Warta R
  • Timmer M
  • Reifenberger G
  • Felsberg J
  • Vallar L
  • Chalmers AJ
  • Herold-Mende CC
  • Goldbrunner R
  • Niclou SP
  • Van Dyck E.

Targeted DNA repair gene expression study in glioblastoma patient biopsies: clinical impact and characterisation of the NEIL3 DNA glycosylase, a novel candidate target for therapy. (Doctoral thesis)

  • Neuro-Oncology Laboratory
March 12, 2019
2019 Mar. Luxembourg: Université de Luxembourg 2019. 156 p.
By:
  • Gobin M.

Therapeutic targeting of Stat3 using lipopolyplex nanoparticle-formulated siRNA in a syngeneic orthotopic mouse glioma model.

  • Luxembourg Center of Neuropathology
March 08, 2019
2019 Mar. Cancers.11(3).
By:
  • Linder B
  • Weirauch U
  • Ewe A
  • Uhmann A
  • Seifert V
  • Mittelbronn M
  • Harter PN
  • Aigner A
  • Kogel D.

Does evidence support the high expectations placed in precision medicine? A bibliographic review.

  • Competence Center for Methodology and Statistics
March 07, 2019
2019 Mar. F1000Res.7:30. [Epub ahead of print].
By:
  • Cortés J
  • González J
  • Medina M
  • Vogler M
  • Vilaró M
  • Elmore M
  • Senn S
  • Campbell M
  • Cobo E.

The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2, a phosphatidylserine flippase.

  • Proteomics of cellular signaling
March 06, 2019
2019 Mar. Biochem J.476(5):783-794.
By:
  • Theorin L
  • Faxen K
  • Sorensen DM
  • Migotti R
  • Dittmar G
  • Schiller J
  • Daleke DL
  • Palmgren M
  • Lopez-Marques RL
  • Gunther Pomorski T.